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Other name of Hay fever is Rose fever 
Hay Fever is the most suffered allergic reaction!

Around 300 years ago, reactions to external agents had begun to attract attention and there were several reports of  such reaction called ‘rose fever’. It was nothing by hay fever and caused by pollen from flowers. Its chief symptoms are sore itchy eyes, runny or stuffy nose and prolonged sneezing.

A patient of the Italian surgeon, Leonardo Botallo (1519-1588), whose patients incidentally included prominent figures as Charles IX and Catherine de Medici, found that rose made him sneeze, made his nose itch, and gave him headaches. He described these symptoms in 1565 and thus became the first person in history to give an accurate description of hay fever, one of the major allergic disorders. Another Italian doctor, Pietro Andrea Mattioli (1507-1577), had a patient who was so sensitive to cats that he became ill on entering a room in which a cat was concealed, i.e. despite being unaware of it.

One of the most interesting and famous experiments to explore the cause of allergy was done in the early twentieth century, which goes by the name Prausnitz-Kustner reaction. Heinze Kustner (1897-1931) was a German gynecologist and obstetrician, who was allergic to cooked fish. He could not eat cooked fish without experiencing itching, skin swelling, coughing, sneezing and vomiting, the reaction taking about twelve hours to settle down. Carl Wilhelm Prausnitz (1861-1933), the German hygienist and bacteriologist thought that the blood of allergic individuals contained a substance which he called reagin (a term modelled on ‘reagent’). This reagin acted with the allergen and produced untoward and unpleasant symptoms. But, the blood of normal individuals lacked these reagins.allowing the body to heal itself naturally and maintain normal functioning.

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